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Tuesday, September 11, 2018

Factors Affecting Bioavailability


In pharmacology, bioavailability is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.  There are many recent advances and factors affecting Bioavailability. It includes Absorption, metabolism and Food effect of Drugs. Physico-chemical factors, first pass metabolism and Energy dependent efflux transporters are also discussed in BA/BE World Congress.
  • Absorption
  • Food Effect
  • Drug metabolism/ biotransformation
  • Energy dependent efflux transporters
  • Physico-chemical factors
  • First pass metabolism
  • CYP450 isozymes





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